How does 5FU(Fluorouracil) work to treat cancer?
How does it work in cell cycle?
We can confirm the RNA and DNA synthesis first, and learn the process of 5FUto treat cancer.
(Reference)
1.Longley D. B. et al. "5fluorouracil: mechanisms of action and clinical strategies". Nat. Rev. Cancer. 3 (5): 330–8.
2.Álvarez, P. et al. "5Fluorouracil derivatives: a patent review". Expert Opinion on Therapeutic Patents. 22 (2): 107–123.
3.Vinayak Singh, et al. Complex Mechanism of Antimycobacterial Action of 5Fluorouracil. Cell chemical biology. Vol 22(1) 2015 page 6375.
4.G.JPeters, et al. Induction of thymidylate synthase as a 5fluorouracil resistance mechanism. BBA vol.1587(23)2002 page 194205.
Music; made by myself, used garageband
Picture(DNA); Pixabay