In this installment of the Synthesis Workshop Advanced Organic Chemistry course, Dr. Yael BenTal joins us to give an introduction to advanced NMR techniques.

This talk has an associated problem set available in the Problem Sets or Courses section at https://synthesisworkshop.com.

References on final slide (references throughout exceed character limit of a video description):

Textbooks:

Chapters 13, 3, 18. Clayden, J., Greeves, N., Warren, S. Organic Chemistry. (Chapters listed are accurate for 2nd edition).

Claridge, T. D. W., High Resolution NMR Techniques in Organic Chemistry.

Hore, P.J., Nuclear Magnetic Resonance, Oxford Chemistry Primer 32.

Iggo, A. J. NMR Spectroscopy in Inorganic Chemistry. Oxford Chemistry Primer 83.

Keeler, J., Understanding NMR Spectroscopy.

Hore, P.J., Jones, J.A., Wimperis, S. NMR: The Toolkit, Oxford Chemistry Primer 92.

Levitt, M. H. Spin Dynamics.

Duer, M. J. Introduction to SolidState NMR Spectroscopy.

Youtube videos:

Callaghan, P. T. Introductory NMR & MRI. https://tinyurl.com/bdcm5vv9

Keeler, J. Understanding NMR Spectroscopy. https://tinyurl.com/2xp7rhyc

Useful resources:

The NMR service at the Hebrew University of Jerusalem: https://tinyurl.com/a3mf3en6

Glen Facey’s blog at the University of Ottawa NMR facility: https://tinyurl.com/mr4897n3

NMR Challenge from IOCB Prague: https://tinyurl.com/mvsh5s2x – structural assignment problem sets

Fulmer, G.R., et al. NMR chemical shifts of trace impurities. Organometallics 2010, 29, 9, 2176–2179. https://doi.org/10.1021/om100106e

Babij, N. R., et al. Further chemical shifts of trace impurities. Org. Process Res. Dev. 2016, 20, 3, 661–667. https://doi.org/10.1021/acs.oprd.5b00417

Torres, A. M. and Price, W. S. Common Problems in solutionstate NMR. Concepts. Magn. Reason. Part A. 2017, 616.
https://doi.org/10.1002/cmr.a.21387