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Video Summary:
Understanding of lung mechanics starts with understanding pressures in respiratory system. In this video I have explained pleural pressure and intrapleural pressure (or simply pleural pressure). Alveolar pressure is pressure in alveoli. When no air is moving and glottis is open, entire airway including alveoli are in balance with atmospheric pressure. So pressure is 0 cm of water. This is the situation just before starting inspiration or expiration. During inspiration it falls to negative value to suck air from atmosphere and during expiration it becomes positive which drives the expulsion of air. Pleural pressure is negative due to opposing force by lung and chest wall on pleural space. Elastic recoil of lung pulls the pleura inward and elastic recoil of chest wall pulls it outwards. Drainage of lymphatics also contribute in vacuum. In this discussion I haven't touched transmural pressure.

Respiratory Physiology Videos:
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• Oxygen Hemoglobin Dissociation Curve:    • Oxygen Hemoglobin Dissociation Curve  
• Factors Shifting Oxygen Hemoglobin Dissociation Curve:    • Factors Shifting Oxygen Hemoglobin Di...  
• Oxygen Hemoglobin Dissociation Curve during Exercise:    • Oxygen Hemoglobin Dissociation Curve ...  
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• Haldane Effect:    • Haldane Effect in Transport of Carbon...  

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DISCLAIMER: This video is for education purpose only. Although every effort is made to ensure accuracy of material, viewer should refer to the appropriate regulatory body/authorised websites, guidelines and other suitable sources of information as deemed relevant and applicable. In view of possibility of human error or changes in medical science, any person or organization involved in preparation of this work accepts no responsibility for any errors or omissions or results obtained from use of information in this video.