Amphetamine can cause psychosis. The psychosis fades quickly for some. But for others, it can persist for weeks or months, or longer. This lecture explores the mechanisms of amphetaminerelated psychosis and the implications for treatment.

‍♀ ‍♂Want to send me a question?
https://askapsychiatrist.info

Chapters
0:00 Amphetamine can cause psychosis
1:02 Chemical structure of amphetamine and derivatives
2:37 The difference between amphetamine and methamphetamine
3:36 MDMA (Ecstasy) links to amphetamine
4:25 What does amphetamine do?
5:47 The first amphetamine epidemic
6:52 The new amphetamine epidemic
8:10 Amphetamine can cause psychosis
9:06 The dopamine hypothesis of psychosis
10:32 Different patterns of amphetaminerelated psychosis
12:10 Having an episode of substanceinduced psychosis is linked to higher risk of later developing schizophrenia or bipolar disorder
13:32 Definition of substanceinduced psychosis
15:33 Does amphetamine just ‘pull forward’ latent genetic risk?
16:55 Amphetaminerelated persisting psychosis has a different pattern of medication response
18:00 Amphetaminerelated persisting psychosis might involve free radical damage
19:57 Amphetamine can activate brain inflammation signals
20:56 Angiotensin receptors may be involved in amphetamineinduced inflammation signaling
21:43 Animal studies suggest benefits from angiotensin receptor blockers
22:23 Case reports of minocycline for amphetamineinduced psychosis
26:24 Risks associated with minocycline