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An Overview of pKas (IOC 41)

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That Chemist (old)

In this episode, I give a primer into pKas, and discuss the best resources for finding pKas for various compounds.

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In the second practice problem, I mistakenly call the Leuckart reaction the Eschweiler Clarke reaction.

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Links to articles discussed in this episode:
Collection of pKa data https://organicchemistrydata.org/hans...
Evans pKa table http://ccc.chem.pitt.edu/wipf/MechOMs...
Baran's book https://books.apple.com/ca/book/thep...
Baran heterocycle poster https://www.scripps.edu/baran/heteroc...
Nparameter database https://www.cup.lmu.de/oc/mayr/reakti...


I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people!

Recommended Texts:
J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations)
T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, WileyVCH Verlag GmbH & Co. KGaA, 2016.
LibreTexts:
https://chem.libretexts.org/Bookshelv...

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