Angiotensin 2 receptor blockers (ARBs) nursing NCLEX pharmacology review for the cardiovascular system.

Angiotensin II receptor blockers mechanism of action works to affect the RAAS (reninangiotensinaldosterone system). ARBs work to lower the blood pressure by inactivating the angiotensin II receptor type I sites. When these sites are inactivated angiotensin II can NOT bind to it, which inhibits vasoconstriction of vessels and the release of aldosterone to increase blood volume.

Angiotensin II receptor blockers are used to treat hypertension, diabetic nephropathy in type 2 diabetics, and heart failure.

Side effects of ARBs include dizziness, hypotension, hyperkalemia, and GI upset. A dry, persistent cough is not common with this medication when compared to an ACEI (ACE inhibitor).

Nursing considerations for angiotensin II receptors blockers include: assessing blood pressure regularly, monitor potassium levels, renal and liver function, educating on lifestyle changes to help manage hypertension, avoid a diet high in potassium etc.

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