ANTICANCER DRUGS, ANTINEOPLASTIC DRUGS, MEDICINES USE TO TREAT CANCER,PHARMACOLOGICAL CLASSIFICATION
LEARN IN DETAIL ABOUT CANCER IN PREVIOUS LECTURE ON CANCER
CANCER PART1 CANCER | PART1 | TYPES OF CANCER | CLASSIFICATION | ETIOLOGY | EPIDEMIOLOGY | PREVENTION | • CANCER | PART1 | TYPES OF CANCER | C...
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CANCER
Cancer is a term used for diseases in which abnormal cells divide without control & are able to invade other tissues
Cancer cells can spread to other parts of the body through the blood and lymph systems
Also called “Neoplasm”
ANTICANCER DRUGS
These are the class of medication which are use in the treatment of the various type of cancer either benign or malignant
Anticancer Also called Antineoplastic Drugs
Drugs acting directly on cells (Cytotoxic drugs)
Alkylating agents
Nitrogen mustards:
Mechlorethamine
Cyclophosphamide
Ifosfamide
Melphalan
Chlorambucil
Bendamustine
ALKYLATING AGENTS
Ethylenimine
ThioTEPA
Hexamethylmelamine (altretamine)
Alkyl sulfonates:
Busulfan
Nitrosoureas:
Carmustine, lomustine, streptozocin
Triazines : Procarbazine, dacarbazine, temozolomide
ANTIMETABOLITES
i. Pyrimidine analogs :
5FU, cytarabine, gemcitabine
ii. Purine analogs:
6MP, 6thiogunanine, pentostatin, cladribine
iii. Folic acid analogs (Folate antagonist):
Methotrexate, pemetrexed
Drugs acting directly on cells (Cytotoxic drugs)
NATURAL PRODUCTS AS ANTICANCER
i. Vinca alkaloids:
Vincristine, vinblastine, vinorelbine
ii. Taxanes:
Paclitaxel, docetaxel
iii. Epipodophyllotoxins:
Etoposide, teniposide
iv. Camptothecins:
Topotecan, irinotecan
Antitumor antibiotics use to treat cancer
Anthracyclines antibiotics
Daunorubicin, Doxorubicin,
Epirubicin, Idarubicin, Mitoxantrone
Bleomycin
Dactinomycin
Mitomycinc
Platinum compounds AS ANTICANCER DRUGS use to treat cancer
Cisplatin
Carboplatin
Oxaliplatin.
Enzymes:
Lasparaginase
Hormones and related agents use to treat cancer
Corticosteroids: Prednisolone, Prednisone
Progestins: Medroxyprogesterone Acetate
Estrogens: Diethylstilbesterol, Ethinyl Estradiol
Androgens: Testosterone
Antiandrogens: Flutamide
GnRH Antagonists (Gonadotropinreleasing hormone (GnRH) ): Cetorelix, Ganirelix, Abarelix
GnRH Analogs: Leuprolide, Goserelin, Nafarelin, Busurelin, Histerelin
ANTIESTROGENS AS ANTICANCER DRUGS use to treat cancer
SERMS (SELECTIVE ESTROGEN RECEPTOR MODULATORS)
Tamoxifen, Doloxifen, Raloxifene
AROMATASE INHIBITORS
Aminoglutethimide
Formestane
Exemestane
Anastrozole
Vorozole & Letrozole
Protein kinase inhibitors use to treat cancer
Tyrosine Kinase, Inhibitors use to treat cancer
Acalabrutinib,
Axitinib,
Crizotinib,
Dasatinib,
Erlotinib,
Gefitinib,
Ibrutinib,
Imatinib,
Lapatinib,
Nilotinib,
Pazopanib,
Ponatinib,
Ruxolitinib,
Sunitinib,
Vandetanib,
Vemurafenib
Pankinase Inhibitors use to treat cancer
Everolimus,
Sorafenib,
Temsirolimus
Monoclonal antibodies prescribe to treat various type of cancer
AntiEGF, EGF2 Panitumumab, trastuzumab
AntiCD20/CD30/ CD52 Brentuximab, ofatumumab, rituximab
AntiCD3/EpCAM Catumaxomab
AntiPD1/PDL1 or CTLA4 Nivolumab, pembrolizumab, atezolizumab, ipilimumab
AntiVEGF Bevacizumab
VEGF, vascular endothelial growth factor.
EGF, epidermal growth factor
EpCAM, epithelial cell adhesion molecule
CD, cluster of differentiation
MISCELLANEOUS ANTICANCER agents
Retinoids: Isotretinoin
Retinoid X receptor antagonist: Bexarotene
Arsenic compounds: As2O3
Adenosine deaminase inhibitor: Pentostatin
Adrenal cortex suppressant: Mitotane
Substituted urea: Hydroxyurea
Proteasome inhibitor: Bortezomib
#कैंसर की दवाइयों की जानकारी,
कैंसर में कोनसी दवाइया इस्तेमाल होती हे?,
#एंटीकैंसर दवाइया कोनसी हे?,
anticancer drugs classification,
use of anticancer drugs,
list of anticancer drugs,
what are anticancer drugs?
medicine for cancer,
#CANCER,
#ANTICANCERDRUGS,
#ANTINEOPLASTICDRUGS,
#CHEMOTHERAPY,
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MR AMAR M RAVAL
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FOUNDER PHARMAROCKS
PHD SCOLAR (GTU AHMEDABAD)
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