In discussion with Dr. Mazyar Shadman from the Fred Hutch Cancer Center, covering the Chronic Lymphocytic Leukemia and Lymphoma key practice changing/informing abstracts from American Society of Hematology (ASH) 2023 conference from Community Oncology perspective. We covered 4 important practice informing studies with Dr. Shadman:
ALPINE: Ph 3, Extended Followup Confirms Sustained Superior PFS of Zanubrutinib vs Ibrutinib for Treatment of R/R Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma
SEQUOIA: Ph 3, Broad Superiority of Zanubrutinib Over BR Across Multiple HighRisk Factors: Biomarker Subgroup Analysis in the TreatmentNaive Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) without del(17p)
SWOG S1826: NivolumabAVD Is Better Tolerated and Improves PFS Compared to BvAVD in Older Patients (Aged ≥60 Years) with Advanced Stage Hodgkin Lymphoma
POLARIX Update: Deciphering the Clinical Benefit of PolaRCHP versus RCHOP in Different Genetic Subtypes Beyond Cell of Origin in the POLARIX Study

#ASH #Lymphoma #CLL #Cancer #2023 #oncology #oncbrothers

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