Neurotechnology and BrainComputer Interfaces are advancing at a rapid pace and may soon be a lifechanging technology for those with limited mobility and/or paralysis. There are already two brain implants, Blackrock Neurotech’s NeuroPort and Synchron’s Stentrode, that have been approved to start clinical trials under an Investigational Device Exemption. In this video, we compare these devices on the merits of safety, device specifications, and capability.

Thanks to Blackrock Neurotech for sponsoring this video. The opinions expressed in this video are that of The BCI Guys and should be taken as such.

ABOUT US:

Harrison and Colin (The BCI Guys) are neurotech researchers and entrepreneurs dedicated to creating a braincontrolled future! Neurotechnology and braincomputer interfaces are devices that allow users to control machines with their thoughts and interact with technology in new ways. This revolutionary technology will change life as we know it, and soon will be as common as the touchscreen on your smartphone. Join us in learning about the braincontrolled future!

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SOURCES

Synchron:

Oxley TJ, Yoo PE, Rind GS, et al. Motor neuroprosthesis implanted with neurointerventional surgery improves capacity for activities of daily living tasks in severe paralysis: first inhuman experience. Journal of NeuroInterventional Surgery 2021;13:102108.

Oxley, T., Opie, N., John, S. et al. Minimally invasive endovascular stentelectrode array for highfidelity, chronic recordings of cortical neural activity. Nat Biotechnol 34, 320–327 (2016). https://doi.org/10.1038/nbt.3428

Soldozy S, Young S, Kumar JS, Capek S, Felbaum DR, Jean WC, Park MS, Syed HR. A systematic review of endovascular stentelectrode arrays, a minimally invasive approach to brainmachine interfaces. Neurosurg Focus. 2020 Jul;49(1):E3. doi: 10.3171/2020.4.FOCUS20186. PMID: 32610291.

I. A. Forsyth et al., "Evaluation of a minimally invasive endovascular neural interface for decoding motor activity," 2019 9th International IEEE/EMBS Conference on Neural Engineering (NER), 2019, pp. 750753, doi: 10.1109/NER.2019.8717000.

C. Pandarinath et al., “High performance communication by people with paralysis using an intracortical braincomputer interface,” Elife, vol. 6,
2017, Paper e18554

Nuyujukian P, Albites Sanabria J, Saab J, Pandarinath C, Jarosiewicz B, Blabe CH, et al. (2018) Cortical control of a tablet computer by people with paralysis. PLoS ONE 13(11): e0204566. https://doi.org/10.1371/journal.pone....

Leuthardt, Eric C et al. “Defining Surgical Terminology and Risk for Brain Computer Interface Technologies.” Frontiers in neuroscience vol. 15 599549. 26 Mar. 2021, doi:10.3389/fnins.2021.599549

Metzger, U., and M. Rothlin. “LongTerm Results with 282 Fully Implantable Vascular Access Devices.” Implantable Drug Delivery Systems, 2019, pp. 50–57., https://doi.org/10.1159/000420749.

Blackrock Neurotech

Blackrock Neurotech. “NeuroPort System Surgical Manual.” 2016.
Bullard, Autumn. “Feasibility of Using the Utah Array for LongTerm Fully Implantable Neuroprosthesis Systems.” University of Michigan, ProQuest Dissertations & Theses, 2019.

Sponheim, Caleb, et al. “Longevity and Reliability of Chronic Unit Recordings Using the Utah, Intracortical MultiElectrode Arrays.” Journal of Neural Engineering, vol. 18, no. 6, 2021, p. 066044., https://doi.org/10.1088/17412552/ac3eaf.

Woeppel, Kevin, et al. “Explant Analysis of Utah Electrode Arrays Implanted in Human Cortex for BrainComputerInterfaces.” Frontiers, 2021, https://doi.org/10.1101/2021.08.28.21....

0:00 Introduction
1:13 Overview
3:02 Safety and Longevity of Devices
5:49 Functionality (BCI Applications)
8:47 Future Prospects and Expandability
9:40 Closing Thoughts