BREAKING: Dr Matt Budoff has now presented the matched analysis for:
KETO (#LMHRstudy) vs Control (#MiHeart)

METHODS – 80 Participants of #LMHRstudy fell within #MiHeart age range and were then matched 1:1 for age, gender, race, diabetes mellitus, hyperlipidemia, hypertension, and past smoking to asymptomatic subjects from the #MiHeart cohort.

PRIMARY ANALYSIS – High resolution heart scans (#CCTA) allowing for primary analysis of Total Plaque Score (TPS), Total Stenosis Score (TSS) and Segment Involvement Score (SIS)

RESULTS
The matched mean age was 55.5 years, with mean #LDL cholesterol of 272 mg/dL (max LDLC 591) mg/dl and mean 4.7 years duration on a ketogenic diet.

There was no significant difference in coronary plaque burden of #LMHRstudy (mean LDLC 272) cohort as compared to #MiHeart controls (mean LDL 123 mg/dl); nb: preKETO LDLC in KETO group was 122 mg/dl

There was no significant difference in CAC (median and IQR) [0 (0,56)] versus [1 (0, 49)], p = 0.520

No relationship of LDLC elevations and plaque

⚠ is still ongoing for second CCTA completion in our cohort by February of 2024. And as always, please continue to work with your doctor.

I will have my own video reaction and thoughts in the coming hours.

to everyone and I mean everyone who helped us get to this pivotal milestone.