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Chemistry of sodium cyanoborohydride and sodium triacetoxyborohydride | Reductive Amination

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Organic Chemistry: Basic and Advanced

In this video the reducing properties of sodium cyanoborohydride and sodium triacetoxyborohydride are discussed with reason. Their role in reductive amination is also explained with examples and mechanism. Both of them are less reactive and more selective than the parent reagent sodium borohydride. Reduction of ketones and aldehydes by them takes place at acidic medium.
Books consulted:
1. Reductions in organic chemistry by Milos Hudlicky
2. Modern Methods of Organic Synthesis by W. Carruthers
3. Organic Chemistry by Jonathan Clayden, Nick Greeves, Stuart Warren

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