Episode 303: Join us on Dadvice TV as Dr. Rosansky and I dive into the latest breakthroughs in Chronic Kidney Disease treatment, specifically targeting how to slow the progression of CKD Stage 3. In this enlightening conversation, we'll explore innovative strategies, recent research, and practical tips to manage your kidney health more effectively. Whether you're navigating the challenges of CKD Stage 3 or supporting someone who is, this video will provide valuable insights into extending the health and functionality of your kidneys.

Main Discussion
1. CKD3 Explained:
* Dr. Rosansky explained that CKD3 is divided into CKD3A (GFR 4560) and CKD3B (GFR 3045). Many people with CKD3A may not even have kidney disease, especially older adults.
* It's crucial to have two GFR values below 60, taken three months apart, to confirm CKD.
2. Protein in the Urine:
* The presence of protein in the urine is a key indicator of kidney disease progression.
* Urine protein levels are classified as mild, moderate, or severe, with consistent high levels indicating significant risk.
3. Importance of Monitoring:
* Regular monitoring of GFR and urine protein is essential. Even a 25% variation in GFR can be significant.
* Patients should ensure their doctors check urine protein regularly.
4. Latest Research and Treatments:
* A recent Canadian study showed that some CKD patients' kidney function improved by 25% over five years, highlighting the variability in kidney disease progression.
* The likelihood of progression to dialysis is much lower for older adults, especially those with minimal protein in their urine.
5. New Medications:
* Dr. Rosansky discussed the benefits of ACE inhibitors, ARBs, and the newer SGLT2 inhibitors. These medications can significantly slow the progression of kidney disease and reduce the risk of heartrelated issues.
* He also mentioned the high cost of newer medications and the importance of evaluating their necessity based on individual risk factors.
6. Diet and Lifestyle:
* Exercise and a plantbased diet are crucial for managing kidney disease. Maintaining a healthy lifestyle can significantly reduce the risk of heart disease and other complications.

Medications Dr. Rosansky spoke about:
1. ACE Inhibitors: ACE inhibitors work by blocking the action of the enzyme responsible for the production of angiotensin II, a hormone that narrows blood vessels and increases blood pressure. Some common ACE inhibitors include:
Benazepril (Lotensin)
Captopril (Capoten)
Enalapril (Vasotec)
Fosinopril (Monopril)
Lisinopril (Prinivil, Zestril)
Quinapril (Accupril)
Ramipril (Altace)

2. ARBs: ARBs block the action of angiotensin II by preventing it from binding to its receptor. This helps relax blood vessels and lower blood pressure. Some common ARBs include:
Candesartan (Atacand)
Irbesartan (Avapro)
Losartan (Cozaar)
Olmesartan (Benicar)
Telmisartan (Micardis)
Valsartan (Diovan)

3. SGLT2 Inhibitors:
Canagliflozin (Invokana)
Dapagliflozin (Farxiga)
Empagliflozin (Jardiance)
Ertugliflozin (Steglatro)
Sotagliflozin (Zynquista)

4. GLP1 agonists:
Dulaglutide (Trulicity)
Exenatide extended release (Bydureon BCISE)
Exenatide (Byetta)
Semaglutide (Ozempic)
Liraglutide (Victoza, Saxenda)
Lixisenatide (Adlyxin)
Semaglutide (Rybelsus)

5. Aldosterone receptor antagonists:
Eplerenone (Inspra)
Spirinolactone (Aldactone)
Finerenone (Kerendia)

Get Dr. Rosansky's helpful book "Learn The Facts About Kidney Disease" at http://go.dadvicetv.com/book

Dr. Rosansky is a highly respected nephrologist and an esteemed author of the book "Learn the Facts about Kidney Disease". With an illustrious career dedicated to the field of nephrology, he has made a significant impact on countless lives through his clinical practice and his insightful writing. His book has served as an essential guide for many patients navigating kidney disease, demystifying complex medical concepts and providing practical advice for managing the condition. Dr. Rosansky's commitment to patient education and his deep expertise in kidney health have firmly established him as a leading authority in the field of nephrology.

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IMPORTANT: This video is intended to be informational only. It is not a medical consultation, nor is it personalized medical advice. This video is not meant to replace a physician's advice, supervision, and counsel. For medical advice, please consult your physician.

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