In this UCSF Neurosurgery Community Grand Rounds, three complex neurooncology cases a thalamic glioma, a recurrent glioblastoma and a low grade glioma are discussed by three panelists: Brian Toyota, MD, Professor and Director, Neurosurgery at Region Medical Center of San Jose and John de Groot, MD, Professor and Chief, Division of NeuroOncology from the UCSF Deptartment of Neurosurgery and Lauren Borate, MD, Assistant Professor, Department of UCSF Radiation Oncology.