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Corey-Bakshi-Shibata (CBS) Reduction

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ChemWis

The enantioselective reduction of ketones using borane and a chiral oxazaborolidine as catalyst is called CBSreduction. It has a very great utility in the synthesis of several intermediates used for the synthesis of natural products. In this lecture, detailed mechanism along with different examples has been discussed.

posted by Kraigherpz