A couple of girls push one of Dexter's pencils into the back of the school bus. Dexter goes to retrieve it; however, a legend says that no one has ever returned from the back of the bus, and Dexter has to find ways to "rescue" himself.

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Past the vaulted doors lives the smartest boy the world has ever seen, Dexter, boy genius! He's constantly creating dazzling, worldsaving inventions in his secret laboratory. His big sister Dee Dee frequently wrecks his experiments. However, he has bigger problems such as his nemesis, Mandark, his brilliant rival at Huber Elementary School. Mom and Dad, of course, have no idea what their little angel is up to.