DIMDiindolylmethane and Estrogen
3,3’Diindolylmethane (DIM)bioactive compound found in cruciferous vegetables, such as bok choy, Brussels sprouts, cabbage, cauliflower, kale, broccoli and radishes.
60% of DIM is derived from the unstable phytochemical indole3carbinol.
Anticancer benefits may come from:
**increased metabolism of estrogen
**generates compounds with antiestrogen properties.
**inhibits or slows androgen activity
**improves cell apoptosis
**DNA repair
**antiinflammatory
Other uses: Acne, PCOS, hormonal balance
There is some evidence that DIM can reduce PSA, estradiol(46%), testosterone (26%) and breast density (5%).
Adverse reactions: well tolerated overall.
Birth control pills, nausea,vomiting, headaches, gastrointestinal distress, diarrhea, dizziness, hyperglycemia, hyponatremia, feelings of thirst, decreased appetite
Forms:
BioResponseDIM increases bioavailability by 50% compared to standard crystalline DIM
Pure crystalline DIMlow bioavailability
Absorption: 24 hours, ½ life is 2.64.5 hours, total elimination around 12 hours.
https://pubmed.ncbi.nlm.nih.gov/24982...
https://pubmed.ncbi.nlm.nih.gov/27261...
https://pubmed.ncbi.nlm.nih.gov/21254...
https://pubmed.ncbi.nlm.nih.gov/27447...
https://pubmed.ncbi.nlm.nih.gov/27671...
https://pubmed.ncbi.nlm.nih.gov/20733...
https://pubmed.ncbi.nlm.nih.gov/32458...
https://pubmed.ncbi.nlm.nih.gov/15155...
https://pubmed.ncbi.nlm.nih.gov/30001...
https://pubmed.ncbi.nlm.nih.gov/25025...
https://pubmed.ncbi.nlm.nih.gov/28560...
https://pubmed.ncbi.nlm.nih.gov/25025...
https://pubmed.ncbi.nlm.nih.gov/20733...
https://pubmed.ncbi.nlm.nih.gov/27261...
https://pubmed.ncbi.nlm.nih.gov/27538...
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DIM
Diindolylmethane
indole3carbinol
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The content of this video is for educational purposes only and does not constitute medical advice. Please consult with your physician before embarking on any dietary changes or taking any nutritional supplements.