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In this part2 video on eukaryotic DNA replication initiation, we discuss the process of origin licensing. This is when cdt1 is recruited by orc6 and cdc6, and helps recruit two double hexamers at the origin of replication. This marks the completion of origin licensing as it moves through prereplicative complexes. We dive into how all this is established and we also connect origin licensing to the cell cycle dynamics as well.

Jump to your favorite section:
00:00 Outline
00:36 mcm proteins
03:12 Helicase assembly
04:03 cdt1 and Single Hexamer
07:14 cdt1 and Double Hexamer

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DNA Replication Initiation videos (Eukaryotes)
Part 1 (Origin Recognition):    • DNA Replication (Eukaryote) INITIATIO...  
Part 3 (Origin Firing):    • DNA Replication (Eukaryote) INITIATIO...  

Complete DNA Replication playlist:    • All about DNA Replication!  

Must watch playlists
All videos on DNA Replication:    • All about DNA Replication!  
All videos on Transcription:    • All about Transcription!  
All videos on Translation:    • All about Translation!  

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