I discussed the drugs which are used in the treatment of urinary tract infection (UTI) and also discussed the pharmacology of nitrofurantoin that is the most important urinary antiseptics that is used in the lower UTI.
Urinary Antiseptics: Nitrofurantoin and Methenamine
UTI Treatments: Antibiotics/AMAs usually are the firstline treatment for urinary tract infections. Which drugs are prescribed and for how long depend on your health condition and the type of bacteria found in your urine. the drugs areTrimethoprim/sulfamethoxazole (Bactrim, Septra, others), Fosfomycin (Monurol), Nitrofurantoin (Macrodantin, Macrobid), Cephalexin (Keflex), Ceftriaxone
Nitrofurantoin Pharmacology:
Nitrofurantoin is activated inside bacteria by reduction via the flavoprotein nitrofurantoin reductase to unstable metabolites, which disrupt ribosomal RNA, DNA and other intracellular components. It is bactericidal, especially to bacteria present in acid urine

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