Electrophilic Aromatic Substitution, starting with the basics of EAS reactions, mechanisms and reactivity, followed by substituent effects including ortho meta para directors and activating / deactivating groups.
We’ll begin with an overview of the EAS reaction and its use in synthesis, what drives the mechanism including stability and sigma complex intermediate resonance.
We’ll look at the common reactions including aromatic halogenation, nitration, sulfonation, friedelcrafts alkylation and friedelcrafts acylation.
We’ll look at ortho meta and para groups and how substituents act as activating or deactivating groups as well as its relationship to directing effects.
And of course, lots of practice to ensure you can follow along
✏ Download the session worksheet and notes on my website: https://Leah4sci.com/orgolive ✏
I’ll email you the session notes right after, or by the following morning
Links from this session:
Organic Chemistry Study Hall https://leah4sci.com/join
Electrophilic Aromatic Substitution video series + Cheat Sheet https://leah4sci.com/eas
Follow along with your semester by using my Orgo Syllabus Companion: https://leah4sci.com/syllabus
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