The cleavage of acylCoA into acetylCoA occurs in four reaction steps: After the initial oxidation of the bond between C2 and C3, hydration takes place. Subsequently, the betaC atom is further oxidized. The final step involves cleavage of the molecule by thiolysis.

Outline:
00:00 Introduction
00:57 Reactions
07:24 Clinical
08:38 Summary

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