Enzyme Inhibition This is the video on various types of enzyme inhibition with suitable examples with NEET PG MCQs and theory questions
00:00 Introduction
00:39 Examples of theory questions
01:10 Enzyme inhibition
01:31 Types of Enzyme Inhibition and Inhibitors
02:20 Reversible Enzyme Inhibition
02:45 Types of Reversible Enzyme Inhibition
03:07 Competitive Enzyme Inhibition
04:29 Enzyme Kinetics of Competitive Enzyme Inhibition
05:17 Examples of Competitive Enzyme Inhibition
05:58 Drugs act as competitive inhibitors
07:40 Ethanol is used in methanol poisoning
08:35 Non Competitive Enzyme Inhibition
09:53 Enzyme Kinetics of Non Competitive Enzyme Inhibition
10:36 Examples of noncompetitive inhibitors
11:17 Difference between Competitive Enzyme Inhibition and Non Competitive Enzyme Inhibition
12:20 Uncompetitive Enzyme Inhibition
13:20 Enzyme Kinetics of Uncompetitive Enzyme Inhibition
14:01 Irreversible Enzyme Inhibition
14:40 Types of Irreversible Enzyme Inhibition
15:12 Substrate Analogue Irreversible Inhibitor or Affinity Labels
15:54 Group Specific Irreversible Inhibitor
17:41 Suicide Inhibition or Mechanism Based inactivation
18:40 Examples of Suicide Inhibition
19:49 Clinical Applications of Enzyme Inhibitors
20:54 NEET PG MCQs
Enzyme Inhibition
Any substance that can diminish the velocity of an enzyme reaction is called inhibitor.
Two general classes of inhibitors are:
1. Reversible inhibitor
2. Irreversible inhibitor.
Different types of reversible enzyme inhibition are:
i. Competitive or substrate analogue inhibition
ii. Noncompetitive inhibition
iii. Uncompetitive inhibition
Irreversible inhibitors can be divided into three categories:
substrate analogue inhibitor or affinity labels
Group specific inhibitors
suicide inhibitor or mechanism based inactivation.
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