https://Leah4sci.com/Grignard'>https://Leah4sci.com/Grignard presents: Grignard to Alcohol Synthesis Shortcuts when reacting with formaldehyde, aldehyde, ketone and ester
Watch Next: Organometallic Reagents and Reactions • Organometallic Reagents and Reactions...
Need help with Orgo? Download my free guide ’10 Secrets to Acing Organic Chemistry’ HERE: https://leah4sci.com/orgoebook/
Grignard reagents are useful for chain elongation of carbonyl compounds in organic synthesis and retrosynthesis questions.
This video will give you tips, tricks, and shortcuts for predicting the specific alcohol products of Grignard reactions with aldehydes, ketones, and carboxylic acid derivatives such as an ester.
You’ll see a quick overview of the mechanism for each of these reactions, with an emphasis on the similarities and differences between the alcohol products, including degree of substitution and symmetry.
Finally, you’ll learn a shortcut for predicting which Grignard reagent was used, when given the product, in a retrosynthesis.
↪ Links & Resources Mentioned In This Video ↩
▸Grignard Series + Cheat Sheet https://Leah4sci.com/Grignard'>https://Leah4sci.com/Grignard
▸How to Tackle Organic Chemistry Synthesis Questions https://Leah4sci.com/synthesis
▸A Simple Approach to Retrosynthesis https://Leah4sci.com/retrosynthesis
⏱ In this video:
[0:32] Formaldehyde + Grignard Mechanism
[1:41] Aldehyde + Grignard Mechanism
[1:57] Ketone + Grignard Mechanism
[2:20] Ester + Grignard Mechanism
[3:57] Overview of Alcohol Products
[4:42] Retrosynthesis Examples
[6:16] Shortcuts for Grignard Retrosynthesis
Follow along with your semester by using my Orgo Syllabus Companion: https://leah4sci.com/syllabus
For more indepth review including practice problems and explanations, come join my online membership site, the Organic Chemistry Study Hall: https://leah4sci.com/join
❓Questions? Ask me here: https://Leah4sci.com/contact
For private online tutoring visit my website: https://leah4sci.com/organicchemistry
Let’s connect:▸Instagram: / leah4sci
▸Facebook: / leah4sci
▸Twitter: / leah4sci
▸Pinterest: / leah4sci
Subscribe to my channel so you don’t miss out on any new videos
https://leah4sci.com/youtube
My MCAT YouTube Channel: https://leah4sci.com/MCATyoutube