Heart failure is a disorder in which the heart cannot pump blood to the body at a rate that is needed causing symptoms of shortness of breath and fatigue. When cardiac output is reduced, when the heart fails, a number of adaptations occur both in the heart and systemically these are early adaption and chronic adaptation.

Ventricular muscle remodelling and hypertrophy and subsequent dysfunction is characteristic of heart failure. There are two broad remodelling processes that occur in heart failure: Eccentric and Concentric remodelling. This is typically known as heart failure with reduced ejection fraction vs heart failure with preserved ejection fraction.

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