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Histology of Adrenal gland Shotgun Histology

Overview of Adrenal Histology
The adrenal gland is encased in a connective tissue capsule that extends septae into the substance of the gland. The organ is richly vascularized and capsular blood vessels, nerves and lymphatics penetrate along with the connective tissue septae.

The most distinctive feature of the adrenal is its partitioning into cortex and medulla. The medulla is fairly homogeneous, but even when viewed a low power, three concentric zones can be distinguished in the cortex:

zona glomerulosa thin, outermost zone
zona fasiculata thick, middle zone
zona reticularis thin, inner zone


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