Dr. Zachary Knight and Dr. Andrew Huberman discuss the development of GLP1 drugs like Ozempic for diabetes and weight loss, examining their historical origins, biological mechanisms, and impact on appetite and metabolism.

Dr. Zachary Knight is a professor of physiology at the University of California, San Francisco (UCSF), and Howard Hughes Medical Institute (HHMI) investigator. Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at Stanford University School of Medicine and host of the Huberman Lab podcast.

Watch the full episode:    • Dr. Zachary Knight: The Science of Hu...  
Show notes: https://www.hubermanlab.com/episode/d...

Timestamps
00:00 Introduction to Weight Loss Challenges
00:06 The Discovery of GLP1 & Its Origins
01:35 Understanding the Incretin Effect
02:58 The Role of GLP1 in Diabetes Treatment
04:39 Challenges & Innovations in GLP1 Drug Development
05:52 Breakthroughs in GLP1 Drugs for Weight Loss
10:47 Mechanisms of GLP1 Drugs in the Brain
13:39 Conclusion & Further Insights

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Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer