How does Warfarin work? Anticoagulant medication via blocking clotting factors 2,7,9 & 10.

Warfarin is an anticoagulant, brand name: Coumadin and Jantoven. This is used to treat and prevent blood clots from forming which may lead to heart attack and stroke patients. Anticoagulant therapy seeks to prevent the development of deep vein thrombosis and pulmonary embolisms.

Time Stamps:
Overview Clotting Cascade 00:00
Warfarin MOA 03:57
When to Use Warfarin 06:57
Important Monitoring Info 09:12
Side Effects & Dosing 13:03
Quick Summary 15:47
Short Quiz 17:04


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Answers:
1.)B
2.)C
3.)D
4.)C

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This pharmacology lecture covers topics such as Anticoagulant drugs. We talk about Warfarin and how it is a Vitamin K dependent antagonist. We discuss how Warfarin blocks the clotting factors 2,7,9 & 10 which leads to less fibrin being formed. This causes the lowering of blood clots. Also, we talk about the pathophysiology of the clotting cascade, heart attack and stroke and how anticoagulation therapy is beneficial. We discuss the mechanism of action of Warfarin and its side effects. Drugs mentioned include; Warfarin, Jantoven and Coumadin.


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