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Knorr Pyrrole Synthesis of Knorr's Pyrrole

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Corrosive Chemistry

In this video I show the Knorr pyrrole synthesis of 3,5diethoxycarbonyl2,4dimethylpyrrole, also known as diethyl 3,5dimethylpyrrole2,4dicarboxylate, also known as simply Knorr's pyrrole.
This is a nice one pot reaction with 32.5g of ethyl acetoacetate, 75mL of glacial acetic acid, 8.7g of NaNO2, and 16.7g of zinc.


  / corrosion  

posted by littlereviewp1