Uncovering Long Term Wegovy Benefits: Insights from Recent Research

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A recent study published in May 2024 unveiled a longterm outcome of Semaglutide, known as Wegovy or Ozempic. This builds on the SELECT trial, which showed Wegovy could reduce major cardiovascular events by 20% in individuals with obesity and no diabetes. Conducted by Ryan et al., the study followed participants for 208 weeks, or about four years.

The primary finding was not a new side effect but a continuation of Wegovy's benefits. Participants experienced an average weight loss of about 10%, maintained over the entire fouryear period. Initially, participants lost weight until around week 65, then sustained this weight reduction for the remainder of the study.

The results are impressive. The weight loss was not just temporary but sustained throughout the study’s duration. This stability contrasts with other longterm studies, such as those with Saxenda, where there is a tendency for weight regain over time. Wegovy’s ability to maintain weight loss over four years underscores its potential as a longterm weight management solution.

Regarding actual side effects, the study found no new or alarming issues. There were no new cases of cancers or other unusual conditions. About 17% of participants stopped taking Wegovy due to gastrointestinal side effects, aligning with other studies of GLP1 medications. This finding supports the overall safety and effectiveness of Wegovy for longterm use.

In summary, this research highlights that the longterm "side effect" of Wegovy is a continued benefit: sustained weight loss over four years. This study reinforces the drug’s role in effective and durable weight management.

Thanks for watching and always remember: small tweaks lead to massive peaks!
Dr. Dan

References Ryan, D.H., Lingvay, I., Deanfield, J. et al. Longterm weight loss effects of semaglutide in obesity without diabetes in the SELECT trial. Nat Med (2024). https://doi.org/10.1038/s4159102402...

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Watch my previous videos about how to fight obesity and about the best medicine for weight loss:
▪ Watch This Before Taking Mounjaro:    • Watch This Before Taking Mounjaro | D...  
▪ From Ozempic to Mounjaro:    • How to Switch from Ozempic (or Wegovy...  
▪ Muscle Loss with Ozempic, Wegovy & Mounjaro:    • Muscle Loss with Ozempic, Wegovy and ...  
▪ Managing Nausea from Ozempic, Wegovy and Trulicity!:    • Managing Nausea from Ozempic, Wegovy ...  
▪ Ozempic: Stomach Paralysis Update:    • Ozempic: Stomach Paralysis Update | D...  
▪ How to Switch from Ozempic (or Wegovy) to Mounjaro:    • How to Switch from Ozempic (or Wegovy...  
▪ Ozempic Paralyzed My Stomach:    • Ozempic Paralyzed My Stomach  
▪ How to Inject Mounjaro: stepbystep tutorial:    • How to Inject Mounjaro: stepbystep ...  

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Disclaimer of Medical Liability. HEALTHCARE EVOLUTION INC. DOES NOT PROVIDE MEDICAL ADVICE. The content of this material is for general informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Reliance on any information provided here is solely at your own risk. Individual medical needs are very different; you should not assume that the information in this document concerning certain courses of treatment or outcomes will apply to you. Rather, you should evaluate your medical condition and make treatment decisions based upon consultation with your physician.

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