Mario & Sonic at the London 2012 Olympic Games is a sports title for the Wii with a Nintendo 3DS version of the game released as well. Both games make up the third installment of the Mario & Sonic series. New sports, such as soccer (association football) and Equestrian, along with other athletic events, debut in the Wii version. The game takes place in London, home of the 2012 Summer Olympics.

The Wii version of the game features 21 total playable characters. These characters are identical to those featured in the Wii version of Mario & Sonic at the Olympic Winter Games.

Like Mario and Sonic at the Olympic Winter Games, Dream Events take place on areas from Mario and Sonic games. Ten appear in the game. Also, some locations have had a rename, but its music is kept the same. For example, the Sky Station Galaxy is the Synchro Battle Galaxy.

Some Items are used in Dream Events and London Party. Buying goodies returns in the game. Costumes make a reappearance in this game. Some of them return from the past installment. Additionally, there are costumes of the playable characters. Most music is taken from the past installments. All rival music except for Dino Piranha, Birdo, Rouge, and Gooper Blooper, for Dino Piranha and Gooper Blooper have their music boss theme from their past games. Birdo's and Rouge's are original. Stickers are the main point in London Party Mode. The first one to get either 16 (about 30. min.), 32 (about 60 min.) or 48 (about 90 min.) stickers win. Players can collect stickers either by winning bonus games and events from characters or rivals, or by obtaining them from bonus balloons.

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