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Mathematics of Insulin by Dr. Om J Lakhani

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Endocrinology India

Mathematics of Insulin Dosing: A Comprehensive Guide

In this video, we delve deep into the mathematics behind insulin dosing, a critical aspect of diabetes management. From the early days of insulin discovery by Banting and Best to modernday practices, the question remains: "How much to give?"

Topics Covered:

1 Insulin use in Outpatient Type 2 diabetes
2 Insulin use in Outpatient Type 1 Diabetes
3 Insulin use in Inpatient Diabetes in ICU
4 Insulin use in Inpatient diabetes in Ward

Key Formulas Discussed:

1 Determining which insulin to use based on FPG and HbA1c.
2 Calculating basal insulin doses using weightbased methods and the0 HolmanTurner formula.
3 Bolus insulin calculations for postmeal glucose management.
4 Total insulin dosing for Type 1 diabetes using the AIM study/Davidson formula.
5 Basal and bolus dosing cycles for Type 1 diabetes.
6 Insulin infusion dosing and transitioning from infusion to basalbolus insulin in inpatient settings.
7 The LakhaniKumar formula for inpatient diabetes in wards.

By the end of this video, you'll have a comprehensive understanding of the mathematical principles behind insulin dosing, empowering you to make informed decisions in diabetes care.

Resources & Further Reading:

Cheat sheet for all the formula discussed in the video: https://www.craft.me/s/LCOuv4fnvvzYZF

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Correction: 13:22 One of the formulas for ICR (ICR = 500 / TDD) or the rule of 500 is not applicable for children or those with low body weight. Hence the example given here is incorrect. It is only valid for adults.


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