In this video, I will explain the rationale behind highdose thiamine therapy as a tool for bypassing metabolic blocks caused by factors unrelated to nutritional deficiency, and examine how this can be a useful therapy for chronic health conditions characterized by mitochondrial dysfunction.

Looking for guidance on addressing thiamine deficiency? Download my protocols here: https://thiamineprotocols.com/

Join the FB group here:   / thiamineprotocols  

Find the full article with references here: https://www.eonutrition.co.uk/post/me...

I have come to the conclusion that one does not need to be deficient (in the nutritional sense) to benefit from this type of therapy, because highdose thiamine is not simply working by correcting nutritional deficiency.

Rather, thiamine is functioning as a metabolic stimulant to restore oxidative energy metabolism in cells that has been inhibited by factors unrelated to nutritional status.

Overwhelming toxicity and chronic oxidative stress have the capacity to inactivate thiaminedependent enzymes involved in the generation of cellular energy, producing biochemical changes which are similar to clinical thiamine deficiency. This could basically be referred to as “functional” thiamine deficiency.

In a functional deficiency dietary thiamine intake is somewhat irrelevant, because the concentrations obtained via the diet are simply not sufficient to overcome enzymatic inactivation.

Instead, extremely high concentrations of thiamine are often necessary to overcome the “metabolic block” and restore the deranged metabolism back to normal. Dr Derrick Lonsdale has discussed this concept on many occasions and laid out the theory in his various writings.

For a clean version of thiamine (TTFD) Purchase Objective Nutrients Thiamax at: https://www.objectivenutrients.com/

Find me here:
Twitter:   / eo_nutrition  
Website: https://www.eonutrition.co.uk/
IG:   / eonutrition  
FB:   / eonutrition