A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: https://kikoxp.com/posts/5084 (dermpath) & https://kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology)

Part 1 of my (in progress) video series about the pathology of melanocytic skin lesions. This video discusses the basic features and patterns that are commonly seen in benign melanocytic nevi, including: symmetry, maturation, basallyoriented melanocytes (i.e. lack of upward pagetoid spread), wellspaced junctional melanocytes (i.e. lack of confluent growth), bland cytology (lack of atypia), and low or no mitotic activity. These are not hard and fast rules, just a helpful framework to serve as a starting point for understanding how to diagnose melanocytic lesions histologically. Exceptions exist for pretty much all of these things. Watch the video to learn more. Many thanks to my awesome medical student, Gray Orman, for transcribing this entire video so that closed captions would be available for viewers who need them!

Topics discussed (special thanks to viewer Ronald Chan for listing these timestamps!):
0:01 Introduction and disclaimers
4:03 Shave biopsy
6:03 Symmetry
9:06 Junctional, Intradermal and Compound Nevus
15:02 Maturation and type A B C melanocytes
26:10 (Lack of) Cytological atypia
34:20 Dysplastic nevus
45:44 Congenital features
1:00:41 Neurotized look
1:02:30 Fat metaplasia
1:03:17 Pseudovascular changes
1:07:22 Hyperpigmentation
1:09:18 Subcutis extension
1:12:09 Nevus vs Neurofibroma

Other videos that will help you better understand this topic:
Normal Skin Histology:    • Normal Skin Histology  Explained by ...  
Melanoma Basics:    • Melanocytic Dermpath Basics: Melanoma  
Melanocytic Immunohistochemistry:    • Melanocytic Dermpath Basics: Immunohi...  

Disclaimers: As I said in the video, distinguishing nevus from melanoma is serious business. My video does not replace the need for getting an expert consultation should you encounter a difficult melanocytic lesion in your practice. Also, melanocytic dermpath has areas of controversy with differing strongly held points of view. by various experts in the field. This video represents MY current views as of April 5, 2018. My views have changed since I started practice, and I suspect (and hope) that they will continue to evolve over time. You (or your mentors) may do things differently than I do. That's ok by me. I'm just sharing the way I currently think of melanocytic lesions with the hope that viewers may find it useful. My goal is to educate, not to create dogma.

This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.

Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.

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