Animation of a computational model of a cadaver knee exercised in a dynamic knee loading machine. The knee loading machine is simulating the motion and forces of a walk cycle. Knee geometries are from MR images of the cadaver knee. The same forces that are applied to the cadaver knee by the machine are inputs to the computational model. The resulting knee motions, both experimental and computational, are compared. This research was funded by the National Science Foundation, as part of the Interagency Modeling and Analysis Group's (IMAG) Multiscale Modeling Initiative. This initiative is administered by the National Institute of Biomedical Imaging and Bioengineering (NIBIB), a part of the National Institutes of Health. Trent M. Guess, Ph.D., University of Missouri Kansas City