Experts discussed squamous cell skin cancer and its various treatments, side effects from treatments, how to prevent future skin cancers, and available patient and caregiver resources.

Topics Discussed
00:00 Welcome and Introductions
02:08 What is squamous cell skin cancer and how it starts
03:37 Epidemiology and incidence
05:03 Risk factors
06:08 Genomics and molecular profiling
08:03 Signs of squamous cell skin cancer
09:09 Diagnosis and staging
12:21 Risk assessment for recurrence
13:22 Sentinel lymph node biopsy
14:22 Treatment and clinical trials
15:13 Firstline surgery
17:36 Nonsurgical treatment options
18:19 Radiation and adjuvant chemoradiation
20:59 Systemic therapy, including immunotherapy, chemotherapy, and targeted therapy
22:34 PD1 checkpoint blockade
25:42 Special considerations
28:38 Research on neoadjuvant therapy before surgery
31:55 Side effects of treatment
33:53 Treatment for adverse events
36:09 Side effects of Immune Checkpoint Inhibitors (ICI), including skin, lung, GI, heart, liver, blood, and neurological toxicities
48:18 Reviewing key points of treatment side effects
48:58 Screening for those who are high risk
51:54 What is advocacy?
52:01 Ways to get involved

Question & Answer Session
56:35 What do you recommend for a young patient who has frequent visits with their dermatologist with an extensive history of squamous and basal carcinoma?
58:51 After several squamous cell skin cancers, does frequency suggest highrisk squamous cell skin cancer? Should I see an oncologist and not just a dermatologist?
1:00:02 If you go to dermatologist and they find something suspicious, do you go to a specialist? How do you know who to follow up with?
1:01:10 Would a patient treated for multiple myeloma have increased skin cancer risk?
1:02:04 What are some basic preventative measures and treatments that target precancer?
1:03:03 What is the difference between niacinamide or nicotinamide?
1:03:22 After many squamous cell carcinomas because of being immunocompromised due to disease, I was given imiquimod which is used for basal cell carcinoma. Is it just as effective with squamous cell skin cancer?
1:04:09 After having Mohs surgery for a large tumor, I still get skin lesions. What are my options?
1:05:41 How do I know when I should contact my doctor if I am having side effects?
1:06:41 Can you clarify if you have HPV squamous cell cancer, are you more likely to get squamous cell skin cancer?
1:08:16 What are the most common questions or concerns from people contacting advocacy organizations?
1:09:32 It can take a long time to get a dermatology appointment. What is the best way to raise concerns?
1:10:50 What are the most common questions and concerns from people who are in treatment?
1:11:57 Conclusion

The Patient Webinar on Squamous Cell Skin Cancer occurred in September 2023. This informational program was created in conjunction with the NCCN Guidelines for Patients® for Squamous Cell Skin Cancer: https://www.nccn.org/patientresources...

The NCCN Guidelines for Patients are available to read and download for free online and via the NCCN Patient Guides for Cancer mobile app. Printed editions can be ordered from Amazon.com for a small fee.

NCCN Guidelines for Patients DO NOT replace the expertise and clinical judgment of the clinician.

Supporters:
This webinar is supported through the NCCN Foundation and by contributions from our corporate supporter, Regeneron Pharmaceuticals, Inc.

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About NCCN Foundation®:
NCCN FOUNDATION® is a 501(c)3 organization founded by the National Comprehensive Cancer Network® (NCCN®)—a notforprofit alliance of leading cancer centers devoted to patient care, research, and education—to empower people living with cancer and advance oncology innovation. For more information or to make a donation, visit http://www.nccn.org/patients/foundation
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About NCCN:
The National Comprehensive Cancer Network® (NCCN®) is a notforprofit alliance of leading cancer centers devoted to patient care, research, and education. NCCN is dedicated to improving and facilitating quality, effective, equitable, and accessible cancer care so all patients can live better lives. Visit https://www.nccn.org/ for more information.

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