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In this webinar, Dr. Yasar TorresYaghi answers questions about OFF time in Parkinson's including symptoms, medications, deep brain stimulation and more. See the time stamps below to jump to a specific question.

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0:00 Introduction
1:23 What is OFF and what are the different ways to manage it?
6:44 What types of symptoms might a patient experience when they are OFF?
9:34 Do OFF episodes have to do with the types of medication you take and your medication schedule?
12:40 Are there any nutritional choices that can play a role in OFF time?
17:37 What is the interaction between OFF episodes and exercise?
20:22 Are there safe ways to extend the life of your carbidopa/levodopa so you have less OFF time?
22:42 Do OFF times increase as Parkinson's progresses?
24:39 What are the most effective ways to treat OFF currently?
29:49 What is your experience with the Neupro patch and does it help with wearing OFF?
31:43 Does strenuous exercise burn through carbidopa/levodopa more quickly, thereby invoking OFF periods?
33:24 When OFF time occurs late in the afternoon, would adding a late afternoon dose of levodopa be as effective as switching to an extended release form of dopamine?
36:19 How much time should you avoid protein before and after eating to allow maximum medication absorption?
37:46 Can you speak to the difference between OFF symptoms and sundowning?
39:48 How much wearing OFF should you tolerate before increasing your carbidopa/levodopa?
41:40 What medications may be coming down the pike that can help with OFF?
43:40 I have OFF times when I don't move much for a long time, is this common?
45:07 My husband has fatigue has fatigue when he is OFF, what can he do?
47:06 If insomnia is an OFF problem, how is that treated?
48:31 Does chewing medication help decrease wearing OFF and what can I take with my levodopa to increase efficacy?
50:17 Does OFF feel different if you're taking a dopamine agonist instead of carbidopa/levodopa?
51:50 Please explain the three kinds of deep brain stimulation surgical treatments?