This lesson includes the procedures to operate the PlasmaCAM CNC plasma cutter machine. Lesson topics include the machine poweron and initialization process, material loading, import of DXF geometry, configuration of machine settings, safety procedures, and performing the automated cutting process. This instructional video was developed by Clark Magnet High School in Glendale, California as part of the Specialized Secondary Program funded by the California Department of Education, and is made available for other schools to use in their instructional programs.