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Oral squamous cell carcinoma - Etiology and Pathogenesis

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Hack Dentistry

Oral squamous cell carcinoma (OSCC), very simply put, is a malignant neoplasm of the squamous cell or keratinocyte. Various factors induce DNA mutations in the squamous cell, causing excess proliferation of these cells leading to cancer.

Trivia:
This video was created in early 2022 and was also the last video (out of at least 100 videos) I had made for HackDentistry. The idea when creating this was to experiment and make an academic tutorial that had a blend of a comic and cinema (through comic illustrations, story telling and background music, though I still feel I could do a lot better). The idea has always been to make learning academic material as fun as possible.

Hopefully I would find the time to make more videos and for free in the near future.

Notes for the video: https://www.hackdentistry.com/bundles...
Notes for OSCC (Clinical features &Histopathology): https://www.hackdentistry.com/bundles...

Website: https://www.hackdentistry.com/
Blog: https://hackdentistry.substack.com/

Study resources on our website
Oral pathology Revision Ninja (Notes, Videos & MCQs): https://www.hackdentistry.com/bundles...
Oral Histology Revision Ninja (Notes, Videos & MCQs): https://www.hackdentistry.com/bundles...
Periodontics Revision Ninja (Notes & MCQs): https://www.hackdentistry.com/bundles...
Question Bank: https://www.hackdentistry.com/bundles...
Access all content: https://www.hackdentistry.com/bundles...

References and further reading:
Scully C, Bagan J. Oral squamous cell carcinoma overview. Oral Oncol. 2009;45(45):301308.
Pires FR, Ramos AB, Oliveira JB, Tavares AS, Luz PS, Santos TC. Oral squamous cell carcinoma: clinicopathological features from 346 cases from a single oral pathology service during an 8year period. J Appl Oral Sci. 2013;21(5):460467.
Sanketh DS, Patil S, Rao RS. Estimating the frequency of Candida in oral squamous cell carcinoma using Calcofluor White fluorescent stain. J Investig Clin Dent. 2016;7(3):304307.
Neville BW, Damm DD, Allen CM, Chi A. Oral and Maxillofacial Pathology. South Asian ed. Elsevier; 2016.
Rajendran R, Sivapathasundaram B. Shafer’s Textbook of Oral Pathology. 7th ed. Elsevier; 2012.
Regezzi JA, Sciubba JJ, Jordan RCK. Oral Pathology: Clinical Pathologic Correlations. 5 th ed. Elsevier; 2007.
Sapp JP, Eversole LR, Wysocki GP. Contemporary Oral and Maxillofacial Pathology. 2 nd ed. Mosby; 2004.

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posted by ukinulag1