How does paclitaxel work to treat cancer?
Which phase of cell cycle does it work in?

(Reference)

1. Microtubules; The basics Molecular biology of the cell 10, 23092327(1999)

https://www.nature.com/scitable/conte...

2.Regulation of microtubule dynamics by TOGdomain proteins XMAP215/Dis1 and CLASP.Jawdat AI Bassam, et al.vol.21 (10)604614 Oct 2011, Trends in cell biology.

https://www.cell.com/trends/cellbiol...

3. Insights into the Distinct Mechanisms of Action of Taxane and NonTaxane Microtubule Stabilizers from CryoEM Structures. Elizabeth H Kellogg, et al. Journal of Molecular Biology. 429(5). January 2017

Music; Music is VFR