Dr. Roger Seheult of https://www.medcram.com/?utm_source=Y...
illustrates the key differences between the various types of penicillin antibiotic medications:

0:57 Discovery and brief history of penicillin
1:44 Penicillinase
2:00 Semisynthetic penicillins (methicillin, oxacillin, nafcillin)
3:21 Need for gram negative antibiotic coverage (Ecoli, pseudomonas, etc.)
4:26 Aminopenicillins (ampicillin, amoxicillin)
4:49 Extended spectrum penicillin (piperacillin, ticarcillin)
5:14 Betalactamase
5:42 Betalactamase inhibitors (ampicillin/sulbactam and amoxicillin/clavulanic acid
6:35 Piperacillin/tazobactam
6:54 Ticarcillin and clavulanate
8:18 Staph aureus and mutations against penicillin (PCN)
8:42 MRSA methicillinresistant staphylococcus aureus
9:14 Clindamycin, trimethoprim and sulfamethoxazole, quinolones, vancomycin, daptomycin, and linezolid
10:13 A note about crossreactivity / low platelets
10:33 MSSA and nafcillin


Speaker: Roger Seheult, MD
Clinical and Exam Preparation Instructor
Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.

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