Acne is a multifactorial inflammatory disease that affects the skin's oil glands and hair follicles. Current acne treatments target the three main factors leading to breakouts: excess sebum production, bacteria growth, and clogged pores. This pharmacology lecture covers topics such as pathophysiology of acne formation, overproduction of sebum, follicular hyperkeratinization, the role of P. acnes bacteria, genetic & hormonal influences (the role of estrogen and testosterone), mechanism of action and side effects of common acne treatments; retinoids, pertinent antibiotics, and hormonal therapies. Drugs mentioned include; Tretinoin, Adapalene, Tazarotene, Isotretinoin, Sulfamethoxazole, Trimethoprim, Clindamycin, Doxycycline, Minocycline, Erythromycin, Azithromycin, Benzoyl Peroxide, Spironolactone, and Oral Contraceptives; Ethinyl Estradiol, Norgestimate, Desogestrel.

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0:00 Acne pathophysiology
3:12 Retinoids
5:55 Antimicrobials
8:31 Hormonal therapy