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  / speedpharmacology  

Benzodiazepines, barbiturates, and sedativehypnotics are central nervous system depressants that work by enhancing the effects of the neurotransmitter gammaaminobutyric acid (GABA), resulting in anxiolytic (antianxiety), hypnotic (sleepinducing), anticonvulsant, and muscle relaxant properties. This pharmacology lecture covers topics such as pathophysiology of anxiety and insomnia, role of GABA in the central nervous system, structure and function of GABAA receptor, limbic system, mechanism of action and side effects of benzodiazepines, barbiturates, and nonbenzodiazepine sedativehypnotics. Drugs mentioned include; Alprazolam, Chlordiazepoxide, Clonazepam, Diazepam, Lorazepam, Temazepam, Pentobarbital, Phenobarbital, Secobarbital, Zolpidem, Zaleplon, and Eszopiclone.

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0:00 Intro
0:28 GABA and its receptors
2:18 Limbic system
3:34 Benzodiazepines
5:18 Barbiturates
6:57 Nonbenzodiazepine hypnotics