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The endocrine system is a complex collection of hormoneproducing glands that control basic body functions such as metabolism, growth and sexual development. Hypothalamus and pituitary gland are the key players in the endocrine system responsible for hormone regulation and production. This pharmacology lecture discusses the hormones secreted by the hypothalamus and the pituitary as well as mechanism of action of various drugs used in treatment of endocrine disorders. Drugs mentioned include: Thyroid hormone replacement agents Levothyroxine, Liothyronine, Liotrix, Desiccated Natural Thyroid; Antithyroid agents Propylthiouracil, Methimazole; GnRH agonists Goserelin, Histrelin, Leuprolide, Nafarelin; GnRH antagonists Degarelix, Elagolix, Ganirelix, Cetrorelix; Gonadotropin replacement agents Menotropins, Urofollitropin, Follitropin, Lutropin, Choriogonadotropin alfa; Corticosteroids Fludrocortisone, Hydrocortisone, Prednisone; Adrenal steroidogenesis inhibitors Ketoconazole, Mitotane, Metyrapone; Recombinant human IGF1 Mecasermin; Somatostatin analogs Octreotide, Lanreotide; Dopamine D2 receptor antagonist Metoclopramide; Dopamine D2 receptor agonists Bromocriptine, Cabergoline; Selective V2 receptor agonist Desmopressin; Vasopressin receptor antagonists Conivaptan, Tolvaptan.

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00:00 Hypothalamus & Pituitary
01:02 Anterior pituitary
02:38 Posterior pituitary
03:24 Thyroid hormones
07:27 Gonadotropins
10:09 Adrenal hormones
11:46 Growth hormones
14:05 Prolactin
15:05 Vasopressin
16:51 Oxytocin