In this video, we will explore the positional system of the brain hippocampal place cells. We will see how it relates to contextual memory and mapping of more abstract features

OUTLINE:
00:00 Introduction
00:53 Hippocampus
1:27 Discovery of place cells
2:56 3D navigation
3:51 Role of place cells
4:11 Virtual reality experiment
7:47 Remapping
11:17 Mapping of nonspatial dimension
13:36 Conclusion


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REFERENCES:

1) Anderson, M.I., Jeffery, K.J., 2003. Heterogeneous Modulation of Place Cell Firing by Changes in Context. J. Neurosci. 23, 8827–8835. https://doi.org/10.1523/JNEUROSCI.23...

2) Aronov, D., Nevers, R., Tank, D.W., 2017. Mapping of a nonspatial dimension by the hippocampal–entorhinal circuit. Nature 543, 719–722. https://doi.org/10.1038/nature21692

3) Bostock, E., Muller, R.U., Kubie, J.L., 1991. Experiencedependent modifications of hippocampal place cell firing. Hippocampus 1, 193–205. https://doi.org/10.1002/hipo.450010207

4) Christopher D. Harvey, Forrest Collman, Daniel A. Dombeck, David W. Tank, 2009. Intracellular dynamics of hippocampal place cells during virtual navigation. Nature. https://doi.org/10.1038/nature08499

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7) Latuske, P., Kornienko, O., Kohler, L., Allen, K., 2018. Hippocampal Remapping and Its Entorhinal Origin. Front. Behav. Neurosci. 11, 253. https://doi.org/10.3389/fnbeh.2017.00253

8) Laura Lee Colgin, Edvard I. Moser, MayBritt Moser, 2008. Understanding memory through hippocampal remapping. Trends in Neurosciences. https://doi.org/10.1016/j.tins.2008.0...

9) Meredith Minear, Tesalee K. Sensibaugh, 2020. Neuroscience of Navigation. https://doi.org/10.1002/9781119458555...

10) Moita, M.A.P., 2004. Putting Fear in Its Place: Remapping of Hippocampal Place Cells during Fear Conditioning. Journal of Neuroscience 24, 7015–7023. https://doi.org/10.1523/JNEUROSCI.549...

11) O’Keefe, J., Burgess, N., 1996. Geometric determinants of the place fields of hippocampal neurons. Nature 381, 425–428. https://doi.org/10.1038/381425a0

12) Robinson, N.T.M., Descamps, L.A.L., Russell, L.E., Buchholz, M.O., Bicknell, B.A., Antonov, G.K., Lau, J.Y.N., Nutbrown, R., SchmidtHieber, C., Häusser, M., 2020. Targeted Activation of Hippocampal Place Cells Drives MemoryGuided Spatial Behavior. Cell 183, 15861599.e10. https://doi.org/10.1016/j.cell.2020.0...

13) Wohlgemuth, M.J., Yu, C., Moss, C.F., 2018. 3D Hippocampal Place Field Dynamics in FreeFlying Echolocating Bats. Front. Cell. Neurosci. 12, 270. https://doi.org/10.3389/fncel.2018.00270

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