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In this lecture, EKG is going to cover protein structure, function, and regulation. First, we're going to break down the structure of amino acids. They are linked via covalent peptide bonds. Next, you'll learn about the four levels of organisation in the structure of a protein and how the specific shape of a protein determines its function in a cell. Third, how proteins fold in the most energetically favourable pathway and what happens if proteins fold incorrectly. Then, you'll learn how proteins work and how protein activity in the cell is controlled and regulated to maintain an optimal state.
Lecture Overview:
0:00 Intro
0:20 Protein Functions Overview
1:09 Protein Structure (Amino Acid)
2:38 Protein Structure (Peptide Bonds)
4:44 Protein Structure (Levels of Organization)
10:55 Protein Folding & Prion Diseases
15:05 Protein Function (How Proteins Work)
19:24 How Proteins Are Controlled (Feedback Inhibition, Allosteric Regulation & Phosphorylation)
✏ All diagrams were made by EKG.
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