Pulmonary Embolism
Instructional Tutorial Video
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URL:    • Pulmonary Embolism  

@4:33 see current guidelines https://thrombosiscanada.ca/clinicalg...

If thrombolysis is required, IV unfractionated heparin (UFH) is preferred. Otherwise, the choice of anticoagulant should not depend on the severity of PE. Anticoagulation should be continued for a minimum of 3 months, after which the risk/benefits of treatment should be reassessed.
Options available:
DOAC monotherapy (apixaban/rivaroxaban).
DOAC (dabigatran/edoxaban) therapy, with initial bridging UFH or LMWH.
Warfarin therapy, with initial bridging UFH or LMWH.
LMWH monotherapy.
Generally, DOACs are preferred over warfarin (lower risk of bleeding), unless there are contraindications.