AlphaFold: Uses and Applications
Speaker: Sami Chaaban, MRC Laboratory of Molecular Biology, UK
2024 Introduction to Biophysical Techniques

In this video Sami gives an introduction the protein structure prediction software AlphaFold. He briefly describes how it works. He details the key outputs of the program and how they can be used to assess the reliability of the predicted structures. In addition to single proteins, Sami describes how protein complexes can be modelled using AlphaFold Multimer. He shows how users can use AlphaFold for their proteins by either downloading from databases of already preformed predictions or how to run predictions on their own sequences. He highlights the potential issues in predictions that users need to beware of. Finally, he illustrates the applications of AlphaFold with examples from his own scientific research and other projects within the LMB.

To learn more about the use of artificial intelligence (AI) in scientific research you can watch the Kendrew Lecture 2021 pt1 given by Demis Hassabis from DeepMind here:    • Kendrew Lecture 2021 pt1  Using AI t...  

To learn about the development of AlphaFold you can watch the Kendrew Lecture 2021 pt2 given by John Jumper, the AlphaFold lead at DeepMind here:    • Kendrew Lecture 2021 pt2  Highly acc...  

Discover more about Sami’s research in the Andrew Carter lab at the LMB here: https://www2.mrclmb.cam.ac.uk/groups...

Read more about software developed at the LMB here: https://www2.mrclmb.cam.ac.uk/resear...

You can find more videos from the LMB 2024 Biophysics Techniques Lecture series here:
   • Biophysical Techniques Course 2024  



About the MRC Laboratory of Molecular Biology (LMB):
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