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Testosterone Replacement Therapy (TRT): What Happens When You Stop?

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Southwest Integrative Medicine

Are you tired of taking testosterone replacement therapy and thinking what happens if I just. Stop taking it. Maybe you just don't want to take it or you don't think it's helping you, but you're worried about side effects or you don't understand what can actually happen if you just stop taking cold Turkey.
So a lot of people are asking the question and want to understand what happens when I stop taking testosterone replacement therapy (TRT). So what I've seen in my practice is that the levels of testosterone will start to rise again, but most people don't wait long enough to see those levels rise.
00:00 Introduction to Stopping Testosterone Replacement Therapy
01:05 Understanding the Impact on Your Body
01:44 WeekbyWeek Breakdown After Stopping TRT
04:12 Concluding Advice and Further Resources
So instead of returning to their baseline or pret testosterone levels, they retest or restart, the testosterone too early. So let me walk you through a week by week scenario of what a typical person is going to feel and what's going on with their testosterone during those times when they stop taking. What happens in the first week when you stop taking trt is basically nothing.

Your blood levels of testosterone will actually be a lot lower in that first week. But at the tissue level, you're still gonna have plenty of testosterone there, and the typical person is not going to really notice. That drop in the serum in the blood because the tissues are still very saturated with the testosterone.

On week two and three of stopping testosterone replacement therapy, you are gonna start to see a decline in the testosterone levels at the tissue level, and with that, you'll probably notice a decline in your energy and any other benefits that you're getting from the testosterone.

Now, when I say energy, I also mean like motivation, cognitive performance and things like that. Maybe you'll start to see about a 25% decline in week two and three, and it's in week three and four that your levels are going to be probably right about at their lowest. This is the point right before your body starts to kick in and increase its own production of testosterone.

That tissue levels on week three and four are basically bottoming out, and you're gonna be at the height of your withdrawal symptoms and Fatigue symptoms. How soon those symptoms come on. And the severity of those symptoms is really gonna depend on how much you were taking, how high were your levels, how much benefit were you getting out of that testosterone and where you started out to begin with.

In week four and five, your LH and FSH levels are gonna start surging, and because of that, your estradiol levels are also gonna go up. Now, if you don't know, FSH and LH are the hormones from the brain that stimulate the testes to make testosterone on the LH side and sperm on the FSH side.

The FSH happens to be an aromatizer. so it also will stimulate more estrogen production. So even though you're producing more testosterone as a result of the surge in FSH and lh, a lot of it's gonna be bound up because you're making more estrogen. And it's, in that week five and six range is when most people are gonna be back to their, pret, pre testosterone treatment levels, back to their baseline, whatever that started out to be.

Now, the reason I say five to six is because there's always gonna be some variance with individuals. It's gonna depend on where your testosterone levels actually started out at, and then how much you are taking to supplement. So if you're taking a huge amount. It's going to feel a lot different than someone that was taking a very small amount to adjust their levels. Some people are gonna have more severe symptoms and feel very, very bad when they stop taking testosterone.

So it really depends on what that variation is between where you started and how much you're actually taking. And if you don't understand that from the beginning, you may want to look a little bit closer at what your levels look like Now, before you stop taking testosterone, maybe you want to just reduce your dose first for a few weeks or even a few months before you just stop cold Turkey.

There's lots of different options out there. Check out my other videos on coming off testosterone replacement therapy , and have another video on understanding your dosage of testosterone.

posted by aber92