The anterior cingulate cortex (ACC) is a region of the brain involved in almost every decision you have ever made. Scientists have long struggled to unify the functions of the ACC, but a coherent theory of its function now seems to be coming into view.


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In this presentation, we’ll see that the anterior cingulate cortex is critically involved in:
Valuebased decisions
Checking progress towards goals
Risk and reward calculations
Integration of values
Autonomic arousal and emotion
Goaldirected actions

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Chapters:
00:00 Decision making and the many roles of the anterior cingulate cortex
06:26 The Anatomy and Connectivity of the ACC
11:25 Thought Experiment: Foraging For Berries
14:53 The dACC in ValueBased Decisions Involving Considerations of Time
19:03 The ACC in Checking Progress Toward a Goal
21:57 The ACC in Risk/Reward Calculations
27:39 The ACC’s role in emotion, interoception, and autonomic physiology
34:56 The ACC controls autonomic arousal and elicits emotional behaviors
41:10 The dorsal ACC Elicits GoalDirected Actions
46:40 Summary & A Hypothesis of the ACC’s Overall Function


Sources:
Monosov, I. E., Haber, S. N., Leuthardt, E. C., & Jezzini, A. (2020). Anterior cingulate cortex and the control of dynamic behavior in primates. Current Biology, 30(23), R1442R1454.

KleinFlügge, M. C., Bongioanni, A., & Rushworth, M. F. (2022). Medial and orbital frontal cortex in decisionmaking and flexible behavior. Neuron.

Pelliccia, V., Del Vecchio, M., Avanzini, P., Revay, M., Sartori, I., & Caruana, F. (2022). 70 Years of Human Cingulate Cortex Stimulation. Functions and Dysfunctions Through the Lens of Electrical Stimulation. Journal of Clinical Neurophysiology, 101097.

King, M. L. (2019). The neural correlates of wellbeing: A systematic review of the human neuroimaging and neuropsychological literature. Cognitive, Affective, & Behavioral Neuroscience, 19(4), 779796.

Talairach, J., Bancaud, J., Geier, S., BordasFerrer, M., Bonis, A., Szikla, G., & Rusu, M. (1973). The cingulate gyrus and human behaviour. Electroencephalography and clinical neurophysiology, 34(1), 4552.

Craig, A. D. (2016). Interoception and Emotion: A neuroanatomical perspective. In L. F. Barrett, M. Lewis, & J. M. HavilandJones (Eds.), Handbook of Emotions (4th ed., pp. 215–234). essay, Guilford Press.


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#neuroscience #brain #decisionmaking