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The optimum pH is the pH where the rate of reaction is at its highest. If you increase the pH above the optimum pH the active site of the enzyme begins to change shape, we call this denaturing.
When an enzyme’s active site denatures the substrate can no longer bind as well, decreasing the rate of the enzymecontrolled reaction.
If you decrease the pH below the optimum pH the active site of the enzyme begins to change shape, we call this denaturing.
When an enzyme’s active site denatures the substrate can no longer bind as well, decreasing the rate of the enzymecontrolled reaction.

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