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The submandibular ganglion lies on the lateral surface of the hyoglossus muscle, medial to the mylohyoid muscle, superior to the submandibular duct and hypoglossal nerve, and inferior to the lingual nerve, from which it is suspended by several branches. Preganglionic parasympathetic fibers derived from the chorda tympani travel in the lingual nerve and synapse in the submandibular ganglion. Some of the postganglionic secretory fibers enter the submandibular gland; others, by entering the lingual nerve, reach the sublingual gland. Postganglionic sympathetic fibers (from the superior cervical ganglion) pass through the submandibular ganglion and are distributed with the parasympathetic fibers.

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